Neural Correlates of Spectral, Temporal and Spectro-temporal Modulation

DEDICATION I would like to dedicate this thesis to my Director and Program Coordinator Dr. Robert Frisina Jr. who has encouraged me and stood by my side in my tough times and to my parents, brother and soul-sister, who have been my four pillars of support through all the high and low tides in my life. ACKNOWLEDGMENTS I would like to express my heartfelt gratitude to my major professor Dr. David A. Eddins and guide Dr. Ann C. Eddins for extending their time, support and technical expertise to guide me through the entire project. I would like to thank my committee member Dr. Joseph P. Walton for his time and contribution towards reviewing my thesis and providing thought-provoking ideas for my future endeavors. I would like to thank my colleagues Darby Blake, Alyssa McElroy, Stefnie Glazer and Shelley West for their help in data collection and data analyses. I would like to thank all my participants for their time, patience and cooperation in completing this study. I would like to express my gratitude to all my friends who have been supporting me through thick and thin and have been serving as a source of energy. I would also like to thank the department and the Graduate School for their support and cooperation in helping me completing this thesis successfully. I finally would like to thank God for blessing me with all the people mentioned above and running the marathon for me. Table 3.1 Spectral, temporal and spectro-temporal testing conditions 21 Table 4.1 Results of three factor, repeated measures ANOVA for SM processing 49 Table 4.2 Comparison of F-value and p-values of different parameters with TM processing 50 Table 4.3 Correlation coefficients of behavior thresholds with N1-P2 amplitude from different clusters for pure spectral modulation 82 Table 4.4 Correlation coefficients of behavior thresholds and N1 latency from different clusters for pure spectral modulation 82 Table 4.5 Correlation coefficients of behavior thresholds and N1-P2 amplitude from different clusters for pure temporal modulation 83 Table 4.6 Correlation coefficients of behavior thresholds and N1 latency from different clusters for pure temporal modulation 83 Table 4.7 Correlation coefficients of behavior thresholds and N1-P2 amplitude from different clusters for spectro-temporal modulation 85 Table 4.8 Correlation coefficients of behavior thresholds and N1 latency from different clusters for spectro-temporal modulation 86 iv LIST OF FIGURES Figure 1.1 Spectral and temporal modulations in time and frequency domains. 2 Figure …